While digital markets offer great profit opportunities, online businesses pose distinctive management challenges, like strong network effects. In this course, we will explore how to successfully navigate these challenges. We will discuss strategies for launching a new online business, strategies for gaining market control, and strategies for the successful evolution of a business. In the last part of the course, we will discuss how market design techniques, e.g., dynamic pricing and reputation systems, can be used to create a well-functioning digital marketplace, and what new business opportunities blockchain technology offers.